We know that ketamine modulates additional receptor types, but the glutamate receptors seem to play the most important role in ketamine’s ability to treat depression and anxiety.
Neurons have a number of different binding sites for glutamate, but when it comes to ketamine, two are of particular interest: the NMDA receptor and the AMPA receptor.
By increasing the level of glutamate transmission while also shifting the balance of glutamate activation from NMDA to AMPA receptors, ketamine rapidly upregulates neuronal production and release of BDNF (brain-derived neurotrophic factor). Aptly called fertilizer for the brain, BDNF is a protein that helps promote the growth, maintenance, and survival of neurons—in other words, it enhances neuroplasticity.
The answer is often yes. Each person’s health profile is unique, and during your video consultation, a clinician will work with you to determine the best treatment plan based on your evaluation and health history. Some medications are contraindicated with ketamine, so please be sure to walk through your current medications with your clinician.
Some Impact clients have been able to safely taper off their anti-anxiety or antidepressant medications under the close supervision of their existing psychiatric providers, following improvements from ketamine therapy.
In addition to ketamine for anxiety, ketamine therapy is backed by research and used by Impact to treat depression.
Ketamine has also been used successfully to treat post-traumatic stress disorder (PTSD), OCD, chronic pain, and is an emerging treatment for other diagnoses.
Ketamine therapy has an excellent safety record.
Impact Psychedelics’s clinical team and board of expert advisors have decades of experience in psychiatry, psychedelic research, and ketamine treatment. The clinical protocols that they’ve implemented ensure that we’re providing safe and science-backed treatment for all of our clients.
Our expert clinicians are licensed, and Impact Guides are equipped with experience and training to lead you safely through the entirety of your psychedelic therapy experience.
Impact has helped hundreds of clients achieve positive outcomes through ketamine therapy.
Using ketamine for depression treatment is 100% legal.
Currently, ketamine is the only legally prescribable psychedelic medicine available, and is available for off-label use for diagnoses like depression. Ketamine prescriptions are given exclusively through Impact Psychedelics’s licensed clinicians.
Learn more about the psychedelic medicine pipeline, and current clinical trials leading to advancements in the field of psychedelic therapy.
Additional integration coaching sessions for $55 may also be purchased
Impact is a mental health and wellbeing company on a mission to help people expand their human potential. We’re increasing access to effective science-backed treatments for anxiety and depression, starting with guided ketamine therapy in comfortable, elevated spaces. Impact partners with licensed psychiatric clinicians to help their clients get the most out of treatment through technology, content, and hospitality-inspired client experiences.
Clinicians on Impact’s platform may prescribe guided ketamine therapy for indications of depression or anxiety. Ketamine is a prescription medication that doctors can prescribe off-label to treat depression, anxiety, chronic pain, PTSD, OCD, and other mental health-related conditions.
It has safely been used as an FDA-approved anesthetic since 1970. At lower doses, ketamine can induce physical sensations and thought patterns described as psychedelic.
You’ll begin with an online assessment and video consult with a clinician to see if you’re a fit. Then, you’ll schedule your first visit where you’ll prepare with your clinician and undergo your first session. Based on your response, your clinician will provide a personalized plan for the next 5 sessions. Throughout your journey, you’ll use Impact’s online platform to help prepare for your sessions, explore your inner mind, and integrate your experiences into your daily life.
Ketamine produces a sense of disconnection from one’s ordinary reality and usual self that may induce or enhance feelings of creativity, purpose, perspective, serenity, insight, inspiration, gratitude, empathy, connection with others and the world, openness to new ideas, psychological rebirth, and traveling outside of one’s self, among others. You may also experience visual, auditory, and other sensory effects.
Please review the safety info on our website for more information about the potential side effects of ketamine.